Live safeing Insulin and Diabetes

Insulin is the medication for diabetes. It saves lives and help patients to maintain their illness.

Here you can find the most important information about insulin and diabetes

Main Information about Insulin and Diabetes

What is insulin?

Is a hormone made by special cells, called beta cells, in the pancreas.

When we eat, this hormone is released into the blood stream where it helps to move glucose from the food we have eaten into cells to be used as energy. Insulin also helps store excess glucose in the liver.

Why must it be injected?

While ways of taking insulin by mouth or as a nasal spray are being developed, they are yet to become readily available. Insulin cannot be given in tablet form as the stomach would digest it, just as it digests food.

What if I have to go on to insulin?

For people with type 2 diabetes, starting on insulin can be a difficult and frightening decision to make. However, the many injection devices and tiny needles available today make injecting the drug much easier than most people imagine. In fact many say that they can feel the finger prick for monitoring blood glucose more than they can feel the needle used to inject insulin. When starting on insulin, your doctor and diabetes educator will help you adjust to the new routine. You may fi nd that even with their help, it may take a while to fi nd exactly the right dose to reduce your blood glucose to acceptable levels and to suit your particular lifestyle.

 

 

 

There are different types available:

Rapid onset - fast acting insulin
Rapid acting insulins are clear in appearance. They are very fast acting, starting to work from 1 to 20 minutes, peaking approximately one hour later and lasting from 3 to 5 hours. When using these insulins, it is important to eat immediately after injecting. Insulin the treatment for diabetes
Short acting
Short acting insulins are CLEAR in appearance. They begin to lower blood glucose levels within half an hour so you need to have your injection half an hour before eating. These have a peak effect at 2 to 4 hours and last for 6 to 8 hours. diabetes and the drug insulin
Intermediate acting
Intermediate acting insulins are cloudy in appearance. They have either protamine or zinc added to delay their action. These insulins begin to work about 1 1/2 hours after injecting, peaking at 4 to 12 hours and lasting for 16 to 24 hours. Before injecting this type of insulin, make sure you check the leafl et inside the pack for instructions on how to prepare the insulin. Zget healthy by using the right drug and medicine
Disclaimer: The information provided on Insulin.asia is for educational purposes only and IS NOT intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek professional medical advice from your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or the use of insulin or any related device.

How is insulin given?
There are many insulin different devices available to inject insulin. The main choices include:
Insulin syringes - Insulin syringes are to be used with insulin vials (10 ml). - Syringes are manufactured in 30 unit (0.3 ml), 50 unit (0.5 ml) and 100 unit (1.0 ml) measures. The size of the syringe will depend on the insulin dose eg: it is easier to measure a 10 unit dose in a 30 unit syringe and 55 units in a 100 unit syringe. • It is best to use each syringe once only. - Needles on the syringes are available in different lengths ranging from 8mm to 13mm. Your doctor or diabetes educator will help you decide which syringe is right for you.

Insulin delivery devices - Devices are available in different shapes and sizes. An insulin cartridge (3ml, containing 300 units of insulin) fi ts into the device. When fi nished, a new cartridge is inserted. Some pen devices, however, are pre-fi lled with insulin and the whole device is disposable. Your doctor or diabetes educator will advise the one that’s right for your needs and lifestyle. - Many people find ‘pen’ devices easier and more convenient to use than syringes. Discuss this with your doctor or diabetes educator. - It is recommended that the needle be changed with each injection. - Needles vary in length. They also vary in thickness (or gauge).

Tips about insulin

Storage - Keep your unopened insulin vials or ‘pen’ cartridges on their side in the fridge. Do not allow to freeze. - Once opened, insulin may be kept at room temperature (less than 30 degrees) for one month and then thrown away. - Insulin can be safely carried in your handbag or pocket. - Insulin may be damaged by extreme temperatures. It must not be left where temperatures are over 30 degrees (remember it can get this hot in the glove box of your car) or in direct sunlight. The drug must not be allowed to freeze. - Variation in insulin absorption (either accelerated or delayed) can cause fluctuations in blood glucose levels. Do not use insulin if: - The expiry date has been reached. - The insulin has been frozen or exposed to high temperatures.

Long acting
Insulin Glargine (Lantus®) is a long acting insulin which is usually injected once a day but can be twice a day. Glargine must not be mixed with any other insulin in a syringe. Glargine pens are available for use with Glargine insulin cartridges. web for Diabetees patients and treatment
Mixed
Mixed insulins are cloudy in appearance. They contain pre-mixed combinations of either a rapid onset fast acting or a short acting insulin and intermediate acting, making it easier by giving two types of insulin in one injection. If the insulin is ‘30/70’ then it contains 30% quick acting and 70% intermediate acting. ‘50/50’ is 50% of each. Before injecting this type of insulin, make sure you check the leafl et inside the pack for instructions on how to prepare the drug.

Are there different types of insulin?

There are different types of insulin ranging from short to long acting as insulin is classified according to how long it works in the body. Some the drugs are clear in appearance, others cloudy.

What is an insulin pump?

The insulin pump is a small programmable device (about the size of a pager) that holds a reservoir of insulin. The pump is programmed to deliver insulin into the body through thin plastic tubing known as the infusion set or giving set. The pump is worn outside the body, in a pouch or on your belt. The infusion set has a fi ne needle or fl exible cannula that is inserted just below the skin (usually on the abdomen) where it stays in place for two to three days. Only rapid acting insulins are used in the pump. Whenever food is eaten the pump is programmed to deliver a surge of insulin into the body similar to the way the pancreas does in people without diabetes. Between meals a small and steady rate of the hormone is delivered. The insulin pump is not suitable for everyone. So, if you’re considering using one, you must discuss it first with your diabetes health care team.

Where is insulin injected?

Insulin is injected through the skin into the fatty tissue known as the subcutaneous layer. You do not give it into muscle or directly into the blood. Absorption of insulin varies depending on the part of the body into which you inject. The tummy (abdomen) absorbs insulin the fastest and is the site used by most people. The upper arms, buttocks and thighs are also used by some people. While it is essential to give each injection in a slightly different spot within the one site (such as the tummy), it is not advisable to change sites without first discussing it with your doctor or diabetes educator.

What affects the way insulin is absorbed?

Absorption is accelerated by:

  • Injecting into an exercised area such as the thigh.
  • High temperatures (eg: shower, bath, hot water bottle, spa, sauna).
  • Massaging the area around the injection site.
  • Injecting into muscle (the deeper the injection into muscle, the faster the hormone will
    be absorbed).
  • Variation in insulin absorption (either accelerated or delayed) can cause fluctuations in
    blood glucose levels.
    pen injection systems for the diabetes drug

Absorption can be delayed by:

  • Smoking.
  • Scarring or lumps due to over-use of the same injection site, which causes the flesh
    to become hard and leads to erratic absorption of insulin.
  • Cold drug (eg: injecting immediately after taking from the fridge).drug application for diabetes patients

Further information about Diabetes on following sites:

Some other links:

Standard Operating Procedure Templates

GMP Consultants

Remedial Fasting

Good Manufacturing Practice

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